Sunday, 6 March 2022

CBBLE UDHC similar cases

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55 year old male  who is a farmer came to casuality with alleged history of seizure activity on 28/2/22 for which he was admitted in a hospital where he was resuscitated and intubated  after having cardiac arrest on day 2 (4 am) of his stay at the hospital.

HISTORY OF PRESENTING ILLNESS

Patient was apparently asymptomatic 6 years back then he suffered with sudden onset seizure activity which lasted for 8- 10 minutes ON 28/2/2022 . 

He had h/o involuntary movements of upper limb and lower limb with uprolling of eyes along with aura ,involuntary micturition and defecation, tongue bite,  post ictal confusion.

He was rushed  to a nearby hospital and was treated conservatively .During the stay in the hospital patient had cardiac arrest on day 2 of admission at 4 a.m. was intubated and put on mechanical ventilator and referred to us in view of of their affordability issues. 

History of fever since 3 days.

PAST HISTORY:

k/c/o seizures since 6 years.

History of trauma to head 10 years back (fall from bike ) ,no chief complaints of LOC, headache, seizures giddiness.

H/o seizure attack 6 years back for which he was treated with levipril.

1 year back  he had another seizure activity since then he was advised to take regular medication ( levipil) to avoid future seizure activity but the patient didn't take regular medication.

Not a known case of  DM and HTN. 

PERSONAL HISTORY: 

Alcoholic since 15 years  , tobacco smoking since 30 years

GENERAL EXAMINATION:

O/E : patient is on mechanical ventilator

         FiO2 - 40%

          PEEP- 5

           VT - 420

          GCS: E1 VT M2

Pallor - present

Icterus  absent

Cyanosis - absent

Edema of feet - present

Lymphadenopathy  - absent

Clubbing - absent

VITALS:

Temperature: 100 F

 BP: 140/80mmhg 

  PR: 112 bpm 

  RR : 18CPM

   SYSTEMIC EXAMINATION:       

CNS:

Pupils -          B/L NSRL

Reflexes:            

      Biceps           2+                   2+

      Triceps          2+                   2+

      Supinator      2+                   2+

      Knee             3+                   3+

      Ankle             -                      -

      Plantar         flexion         flexion

CARDIOVASCULAR SYSTEM : S1 and S2 heard, no murmurs heard 

RESPIRATORY SYSTEM : BAE present

P/A : soft

INVESTIGATIONS:

5/3/22

BGT: B POSITIVE



6/3/22

SPOT URINE PROTEIN: 7

SPOT URINE CREATNINE: 74

RATIO: 0.09



PROVISIONAL DIAGNOSIS:

 SEIZURE UNDER EVALUATION (? ALCOHOL WITHDRAWAL SEIZURE)  ? HYPOXIC ENCEPHALOPATHY POST CPR STATUS DAY 5 

TREATMENT

HEAD AND ELEVATION UP TO 30%

INJ. MEROPENEM 1 G IV BD

 INJ. LEVIPIL 500 MG IV BD 

INJ MIDAZOLAM 10 MG IN 50 ML NS @ 30 ML/ hr INJ. MANNITOL 100 ML IV BD

INJ. PANTOP 40 MG IV OD

INJ. NEOMOL 100 ML IF TEMPERATURE >  101 F INJ THIAMINE 2 AMP  IN ONE DNS IV BD

SOAP NOTES:

DAY 2(7/3/22)


S:- Fever spikes present  

O: patient is on mechanical ventilator

          PEEP- 5

          FiO2 - 40% 

          VT - 400ml

          VITALS:

temp- febrile

BP 140/80 mm hg 

PR 130 bpm. 

RR 18 cpm 

spo2: 92% with Fio2 40%

CVS - S1, S2 heard ,muffled heart sounds

RS. :- NVBS Present, no crepts

P/A: soft, non tender 

CNS: Pupils :B/L NSRL 

REFLEXES :     right             left 

       Biceps.          2+               2+

       Triceps          2+               2+

       Supinator       2+              2+

       Knee               -                 - 

       Ankle              -                -

       Plantar          mute            mute

A:- Seizures secondary to ? tuberculoma /NCC ?alcohol with hypoxic encephalopathy with post CPR status day 7 , mechanical ventilator day 6


Day 3:(8/3/22)
S:- no fever spikes

O- O/E : patient is on mechanical ventilator
          PEEP- 5
          FiO2 - 40% 
          VT - 400ml
          Timp : 2.1
          VITALS:
temp- afebrile
BP: 110/90mm hg 
PR: 115 bpm. 
RR: 16 cpm 
spo2: 99% with Fio2 40%
GRBS: 168 mg/dl
CVS - S1, S2 heard ,no murmurs
RS. :- NVBS Present, no crepts
P/A: soft, non tender 
CNS: Pupils :B/L NSRL 
GCS: E1VTM2
Cough reflex present
corneal reflex present
conjunctival reflex present
REFLEXES :      right         left 
       Biceps            2+             -
       Triceps           2+            2+
    Supinator          2+            2+
       Knee              3+            3+ 
      Ankle               -               -
      Plantar            mute       mute

A: Seizures secondary to ? tuberculoma /NCC ?alcohol with hypoxic encephalopathy with post CPR status day 8 , mechanical ventilator day 7

P: ENT opinion i/v/o tracheostomy

Day 4:(9/3/22)
S:- fever spikes present

O- O/E : patient is on mechanical ventilator
          PEEP- 5
          FiO2 - 40% 
          VT - 400ml
          Timp : 2.1
          VITALS:
temp- 100.9 F
BP: 120/90mm hg @ NORAD 6ml /hr
PR: 114 bpm. 
RR: 16 cpm 
spo2: 99% with Fio2 40%
GRBS: 129 mg/dl
CVS - S1, S2 heard ,no murmurs
RS. :- NVBS Present, no crepts
P/A: soft, non tender 
CNS: Pupils :B/L NSRL 
GCS: E1VTM1
Cough reflex present
corneal reflex present
conjunctival reflex present
REFLEXES :       right                  left 
       Biceps             2+                     2+
       Triceps            2+                     2+
    Supinator           2+                     2+
       Knee               3+                     3+ 
      Ankle                -                        -
      Plantar             extensor            extensor

A: Seizures secondary to ? tuberculoma /NCC ?alcohol with hypoxic encephalopathy with post CPR status day 9 , mechanical ventilator day 8


Day 5(10/3/22):
S:- no fever spikes 

O- O/E : patient is on mechanical ventilator
          PEEP- 7
          FiO2 - 40% 
          VT - 400ml
          Timp : 2.6
          VITALS:
temp- Afebrile
BP: 90/50mm hg @ NORAD 8ml /hr
PR: 109 bpm. 
RR: 14 cpm 
spo2: 99% with Fio2 40%
GRBS: 181 mg/dl
CVS - S1, S2 heard ,no murmurs
RS. :- NVBS Present, no crepts
P/A: soft, non tender
CNS: Pupils :B/L NSRL 
GCS: E1VTM1
Cough reflex present
corneal reflex present
conjunctival reflex present
REFLEXES : right. left 
       Biceps   2+                   2+
       Triceps . 2+                  2+
    Supinator  2+                 2+
       Knee        2+              2+ 
      Ankle      -                  -
      Plantar    extensor    extensor

A: Seizures secondary to ? tuberculoma /NCC ?alcohol with hypoxic encephalopathy with post CPR status day 10, mechanical ventilator day 9

Day 6 (11/3/22):
S:- no fever spikes 

O- O/E : patient is on mechanical ventilator
          PEEP- 7
          FiO2 - 40% 
          VT - 400ml
          Timp : 1.9
          VITALS:
temp- Afebrile
BP: 140/80mm hg @ NORAD 10ml /hr,vaso 2ml/hr
PR: 73 bpm. 
RR: 14 cpm 
spo2: 99% with Fio2 40%
CVS - S1, S2 heard ,no murmurs
RS. :- NVBS Present, no crepts
P/A: soft, non tender
CNS: Pupils :B/L sluggish reaction to light
GCS: E1VTM1
corneal reflex present
conjunctival reflex present
REFLEXES : right. left 
       Biceps   2+                   2+
       Triceps . 2+                  2+
    Supinator  2+                 2+
       Knee        2+              2+ 
      Ankle      -                  -
      Plantar    extensor    extensor

A: Seizures secondary to ? tuberculoma /NCC ?alcohol with hypoxic encephalopathy with post CPR status day 11, mechanical ventilator day 10
P: MRI

Day 7 (12/3/22):
S:- no fever spikes 
O- O/E : patient is on mechanical ventilator
          PEEP- 6
          FiO2 - 30% 
          VT - 460ml
          Timp : 1.9
          VITALS:
temp- Afebrile
BP: 150/70mm hg 
PR: 79 bpm. 
RR: 17cpm 
GRBS: 149mg/dl
spo2: 99% with Fio2 30%
CVS - S1, S2 heard ,no murmurs
RS. :- NVBS Present, no crepts
P/A: soft, non tender
CNS: Pupils : NSRL
GCS: E2VTM2
cough reflex: present
corneal reflex :negative
conjunctival reflex: present
doll's eye: negative
REFLEXES : right. left 
       Biceps   3+                   3+
       Triceps . 3+                  3+
    Supinator  3+                 3+
       Knee        3+              3+ 
      Ankle      3+                 3+
      Plantar    extensor    extensor

A: Seizures secondary to ? tuberculoma/?NCC with chronic hypoxic encephalopathy with post CPR status day 12, mechanical ventilator day 11
P : EEG

Day 8 (13/3/22):
S:- no fever spikes 
O- O/E : patient is on mechanical ventilator
          PEEP- 6
          FiO2 - 25% 
          VT - 400ml
          Timp : 1.9
          VITALS:
temp- Afebrile
BP: 130/90mm hg @NORAD 4ml/hr
PR: 112 bpm. 
RR: 14cpm 
GRBS: 157mg/dl
spo2: 99% with Fio2 25%
CVS - S1, S2 heard ,no murmurs
RS. :- NVBS Present, no crepts
P/A: soft, non tender
CNS: Pupils : NSRL
GCS: E2VTM2
cough reflex: present
corneal reflex : present
conjunctival reflex: present
doll's eye: negative
REFLEXES : right. left 
       Biceps   3+                   3+
       Triceps . 3+                  3+
    Supinator  3+                 3+
       Knee        3+              3+ 
      Ankle      3+                 3+
      Plantar    extensor    extensor

A: Seizures secondary to ? tuberculoma/?NCC with severe hypoxic ischemic injury with post CPR status day 13, mechanical ventilator day 12

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